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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f525180a966ce0e573e94174b805cd41f87b3e5b1bd0746e5661c56b687cffc1' 
  AND token = 'iPVx3IbPO7TTzyFWrZ7AwYnQKQhUHD4cP+SUtM1c37Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}