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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5416c4f4ce7d39c3ac18590f1e30b699e4178e00d4a43322d35553fa2f1aa34d' 
  AND token = 'lo2zrl8oXlRWmV+Mmfztqg9Bp9So4kWQ36/1nVIiHek=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}