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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45bc6bbd43adce603ee495f102578c338d9cc222fe7205e781c2ef8c3a807351' 
  AND token = '+JDwwS0MDJGtUg4LmyzBETmE5TL+j021Ma5IzqWuKg4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}