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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c12d8157ce0dfec5952b51740fa11a9ccabb0797a6b24af628341e8e67732e14' 
  AND token = 'GNFjlLU2Nmz48YZxHzB95Gd9oQDWnexF63wOboccg/o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}