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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d5e0a341ddd18b6d4a35fbb9120feb6b61a80709101c0a57c6b856ca23e74d6' 
  AND token = '16cNdkN8rqEbD9O6wD2GFsqfuJEfWpIRJ/NGaZFNo/U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}