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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5ea161b1490207361f2636f8db84b96bbabcca5873cb3d023ca728f3ac4d07e' 
  AND token = 'VQIBfIL5t7S4kU6Yzb0DooLUnv/V8rDEo6izbMF1Agk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}