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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad7d2ba414ab911e15313a56b793b826065677dbb2ef99485f9c74d04a867f23' 
  AND token = 'NBovloelfnwTPnldWJi0K0diXljHrotHcraMPoO6nMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}