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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '69d921dfe9195abd8392beaabd0202ed7ab398652bcf2262d422ceaff24e4fb2' 
  AND token = 'gdcwnPxaeIGl/NNKBy59S5Z4k4Z4omjUkUlC8Q7gm7c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}