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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4619ee5f409a61146c1f0de3fef432980f41c14727fcfc0b4ea8181c868ba149' 
  AND token = 'GseGwPSwmYS69aad+M27TY+Nr3W0MJA4jofURGYlBgc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}