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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b286856167fbc70067cefcd7052406f3c7e475f10c39c3ce354b87a8a06e3c6' 
  AND token = 'iQ1L245oG4mrB9Ov3Y2eYpIS/gZr6UlMZKxY0c9359Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}