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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1de767bb23ba20a0893b4a1285ac1afddfa4814fe0ee522bb8978299b65c027' 
  AND token = 'ZdMuTR06Sh8LiI8nln6Q+XYY7t/CHzkb1Jahs6sV+uM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}