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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '45d6f7a07e2cd486244cfdb25343910997220d0c4dbd2abb8f5dbc4f8ab6f9c6' 
  AND token = 'yZbT/HXeR9XzfuM0F/hTC5ShMl119O+s76dYIGLU0Lg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}