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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '800f48085bb6ee5757ea8a45625e5e1fae880fac3dc4984e253318264a9d63f4' 
  AND token = '8xycJvvCMb294KTeAfCdtcLGLLkJawwa+SvQ65sAi9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}