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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c1ce6fcb1dffb9b232f721b73a05627ce97be77209507e971e4db08f5a936633' 
  AND token = 'cySap6dyCzhChOy39ZtO79a586WIEMtRJMdE+JBtbYE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}