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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5948aac0e326f71f3e594c198eaf3bcb33bda68dfbe97c0743bccd8a2b5ac47c' 
  AND token = 'eR0tNKg1NH9EMv86GXsaDzw+MHsnvfwr7Dc/K8fSkDg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}