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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f983380459132959d3b8e3fb2f0c1aad5fd9643a94099a0c19916fb560798894' 
  AND token = 'ECh3exSPrtW9Wu7DHooMneBTXSU4AiEwHYB+Ke2WqLM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}