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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74f909e7dc9816510da42f69c37be35d243733e7401f54d94a33165c92305c40' 
  AND token = 'po2s08N+PH9NfhrOZ3RqKQQ6a3iXtBVliUwEZ9kLMjY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}