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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '33743ca07ba977985f8bacb9815304281a4b9ccb10fa0753c54d2021e2f9373b' 
  AND token = 'TO45s8iiL1aJwDETHEx2H2SGDFI5gEhxNp2r4DhrJE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}