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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43c001e1ac7269234b98e520ab990df5a06568781d56698a609c1f94c053b932' 
  AND token = 'feRD/GrEYvhn0tqTGJNvnUj7BEPcP2XYSRGOEloHlQM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}