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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0dc4845c4732ee217102ded80945a5955608bb8d8c8b4f330f3539c19da5d4' 
  AND token = 'bj7G1G+qaSY8fYQKhwyUtVpGpH8oUZRoSTW4G8d9dvM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}