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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '14082760aeaef992a235cab8026a246c8453be35657291797ee2423780d661e6' 
  AND token = '1L9NXIKvH/sZT2ydHtkdxcbAAjTBia6p8MRk3Ju9jf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}