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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6473d5e2568c47fcccd32115f8da62b13791a65a887312853c35a8b1c0c85c32' 
  AND token = '9DkpsD2fCOSHhZNFy/V9aYqVbWzI0opqxSTG9F0HKW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}