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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '331357c6c0079d34ce5e4a4d3524b826da528219ad78946d6498314973c5e02b' 
  AND token = '+9CK66kcnE94tSQqgJRkFNoCAeGA+3YZn1UBB2p+S+c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}