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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d307a0a41536f0cb932f61edbd3412c66c1e42e41c147eee13876e6877e6cd5' 
  AND token = 'zfeti6wRMQhB0/cioJdud/FMPWoeeqBBf0+94ho329Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}