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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4eeee891dc398a14784d9187a1bbfedad1edad05014a7177487f14fc835b9a7a' 
  AND token = 'qoeF3y4/C0ijL8tExDTsJVCqSNh1hdHgrm+9rfoIL1Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}