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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d4c4dee3e1a79475277b8b7a66651a492897962046bbb62160901cd61725f0e' 
  AND token = 'V81OoczC8LGo5blDW/SUe7XGixTiAjIDoo95sdR7gTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}