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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e47d3fab7f67de7161e0d0f9990666ada21cca2415f21a6070f97cded2a0d300' 
  AND token = 'H56NGuS7JdBq/lmdYhZItj2oDdvxXM6N4cmNoDAx8+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}