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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '414bccbb84fdd9f76a53f76d066ebeab8091b6a23bdd3830bf719a8dc1caa49b' 
  AND token = '+Ihjh3Pu2AVh2+Vmtpfamh7zMrr8+YMk9wU1tocrIw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}