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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7081559b256fe39bf74059e0b24ed905ea819dbbc8defcf854a702cce52ff55' 
  AND token = '8K2pzwFH3Yg0k/xO25/714TlyUkkCU4M0sgOzLW86KA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}