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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '75656def80f45983aa5ed5accd45a58e1db4e2f94b33b85ba7555d9b11447c55' 
  AND token = 'HmPbIZnRRIO482nsa4QkZpXD0sxmxzMRva5yj6gA2AE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}