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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72027630c4fce8afdab886656c93fb4be8641be5604102005770b2fc42dff013' 
  AND token = '3w0RLDz4qHqUsyfxxJSP6IOCnHCHH9b7UnOPZxY/mno=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}