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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5ac40678b1154469c7aff19ec40f6bcc3dfc3e3f61da59a650f5e25a2fae3f4e' 
  AND token = 'CUcmnz7wMGjNA3pG23fOOsgUd5q9nbQrHJbOGD/qdm8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}