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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '944c9e5650329a0a3d1f143a325142c59e44eac8547c868213b48a6ca52bda3d' 
  AND token = 'GIj4AgUOmNzAT0hR7QoQkTkMXOT2urxuiy1mo6R5cAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}