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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5acbffdd0e14e3025b887a232388f125a9f07e703d3ed89131add6e3a8533e6b' 
  AND token = '15DTq9+gu5CUK7DwBd+2QvshPZA5VMnUxaUgSbeDFuM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}