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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '17d0b1a82f7755b3a2e40f762e639d7c79721da92d5c26f8e3816a5e99569aa2' 
  AND token = 'IkDMQvefCJQ9qdcVwOpyBKk3lI6bO/pi/2nZv6PkLzw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}