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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '15d5e35ac48ede433a6e081079fc3443e8f7157d05e52e67b5ae22943e087c77' 
  AND token = 'NislEl6uB+jJzhdN7B1brrgWKJk8a7yRLG3GhumOKQo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}