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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f5817918cb324d96cd03ec317ae6c8523ca28526c74ee9ca710f69917934483' 
  AND token = 'SsS64S3fJiNykKdlwg+jEODI+JG5yF+RrTnXekVudRk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}