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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4924c8d79532b6e21b843040e2aad67bfd2d50e71fd51e46f0e186af2af1363a' 
  AND token = 'jp1b2bP8WlDYWbaeIZ8CkGWCXQIRF6IygjW7mPJBrWE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}