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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6b54f59d46a7477cd0636649a9189b56db421feec8306f7d5ee23b64ae1e154' 
  AND token = '4b3SfWeeGUmmY3WIUivq4WPOcCzMjxnOyuLOc9Fg1Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}