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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b25274735c83cca04961284fa4240b5b102b026b3abfbfb669e276c0a8909360' 
  AND token = 'tsvBNJqqiX15AFU6FrM04VxBh3rzZYQbYcxnh5CMfFA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}