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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ff6a5c3b6eb888fc4eeb7b15617c3f69979104a3bae202a993875abe00ba454' 
  AND token = 't4uqe/B3+yxnGoWrVtDdmj5cnV17sL9ShnN1Y/UERe0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}