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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '50767e2e353448259f34f2bd097638ff160ff4504bd4a0c0df529ac17a514083' 
  AND token = 'q1kh9BSs2ck1HolF7069OvA/g2Mmbfj/yh5NGlg4ve4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}