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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd75c68a380096c8ca3b3724f4dfbe31a720f915f104fb971ff0ce67436b32a7c' 
  AND token = 's6WDQjWhrhPJ2a2qv+w1OWEHBc1G9FvVWQW8baRiOX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}