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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb78001d3aab2977904b49edbc8294359dce61806b05f30356923734589ccead' 
  AND token = 'bcdYtdpx7LkqlMqgAAickR14pOlpB0rRpBw3E6r1B5w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}