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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89dc34efb562168cef2b469ecd889ea2d8c5744a939406f66e45523b51039325' 
  AND token = 'FWsiK6+PJjs33wd95Ax+iG7+ueG2lAdlRZe+oL9yV/4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}