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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e591e0dbd7fa3b266ae8d228df5283f712862e07883e58bda035f3639530df7' 
  AND token = 'hSF5CirdUyxEoFZW5yb7TYbjkvmTZW+pBFe9pwvQZdw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}