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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4faa1e7db2d7d190174779473b2a8fdc26c01b8eab60df40053ad586948b041' 
  AND token = 'C10/tG3PyWS7Oze01GQ+rcilyUS5zInAU+GL2nwzgaI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}