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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fabb251011606178c51803f854c359335768ddde1eb847c25c680f27e3f3000a' 
  AND token = 'S003T32Z6l/cPzZm39qGZIhRAmkGn31IWK4Pzpr18Kc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}