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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9e4c73a67b4461c70a8fa15f94b46622a00abbc0d73f1bcfca2767d9780907a' 
  AND token = '+m6V799m/bRz/kscYn8SgRmRLR3rYqRpZOdlRfDEew8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}