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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '709db0097759d9ed8de33335bd2bbad9fc88aac4a2e78f66623428008e346d0b' 
  AND token = 'dKAnp1BnVk+pru09zRhTtn5MDqawYzY471HjGu6i7zI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}